SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459b6ac19919fafe50c186b96e347aca20e1b08626294f692b4a5f1662f8f3a1' 
  AND token = 'Ld+yjC4CM4NwqxpUk9n5CqeC9W/a/7cw6epZ9CCysiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00063

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}