SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36576082a7b86bd7ab17a150d627d24a72d87638d7e09d5bcc2fdf73ccafc009' 
  AND token = 'K8HMFb7OGz188m/K0+t9WDi1Zp+6gHPyGbo+b0D6igY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}