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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57503c08aae1efc07f669289b1b84cf4f9f1ff65b8b84179826991a9bc1aa85b' 
  AND token = '8kKJpyjALlt6tywjCiJg3ujKAF59rf3Lh1aYZsj0ENI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}