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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e5a1abacd88484d86fe48145e589209dae8b8716855c733b658a080ccc6708a' 
  AND token = 'f9QZfUk2TlfKbDF54e3inaQ4C3SwBc+0ibYcLg15NZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}