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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50201e8c32f98d26f0411e50c15f8b589d4c4dedf700d7ab9bd8446b2c8110d6' 
  AND token = '/uBVt0OPxE1Xf+eoFFr2tvsVQRQZ2/UVqGhJWYiErME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}