SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f44de445761ebcdf8e9dd2625bb5fc020454b56326481263fe59967ed4caa766' 
  AND token = 'UG9tYroVuA7DR5zJjdXbEz7aVP868TN2R+BDJdTaad0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}