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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0140a9138b2dc8d93d4b69517689c9228d9240847a83ecc99b21f32faaa39321' 
  AND token = '+JPh4Qn4lom1EMwQh48ELDirB7jEjLTJPI+wyFksU7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}