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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e33222910b58c1335cc4b013d50d1342c37b8b6d88a382e0967755c458759f27' 
  AND token = 'BKFS0gWy3oIRuknoYSt86Jq+iWVEii6y7M4S6wBdXkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}