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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e0f9214ba4f395bd4ae8e7f0938c9f918a0497955449f9ac4d3c13a17f9d01c' 
  AND token = 'utaIXcj4hi8YCaoTE2uwKBmc02/MzdnOoShisvbB4sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}