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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '515517f00e7301d81f79dc5bdfdfb4595b317c732f8bdf15fc071f1020821f2d' 
  AND token = '6k5oAvXZmy6UrNgcE750NwndTW3Z0FiKUf+HZ8Vh2cs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}