SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e2c7ce65103e0d579235c67f2f3a5579573c6189bc884f201b8bfa06e453e9' 
  AND token = 'ynopRz/xF0FmI2wo+au850Dwxg8uuTBrq7fB+7nqmCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}