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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '001d0c230385ddadd28a5307f0055c13c75dc6bd16c3fdc37a7fef22e420aec2' 
  AND token = 'XEAj+6kDnREyDebvfw19sFHW20jUFK5RkocM1LQCvLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}