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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9940d2a197cf298e3b085be9b28648e3d8638e0dcd5ca7eb4ed4837dd6215f47' 
  AND token = 'EvT+v2ppPeGKoGn+PyAqRZ2C3N+zdYyceglDyXSCUNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}