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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4ccd1dc1488e2c2a10477a17ba44aa8e52d37cfffeefba37ad267169b59e2d' 
  AND token = 'BbA/dvpih40YprNXQurcNXojAc8CxOmutptJm78BG5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}