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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1735cb53a087889ec655e64fdfe3a76bc0f302f695f29ac550affab4f78bab1' 
  AND token = 'cndAW2c9s+y0iC0xIjOVAZ3/d2BjjA1pY6PE6aPnfEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}