SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea5b740863b5edf42364b4090536e3f30edfb7196333d0289d9d60695243934e' 
  AND token = 'vN9kGj2rg6Lbs8vfGb75YJUYpeKcR1cBgLzZs2nBQ50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}