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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f532f3917a873105f71439c3b9346a7533d35eb7b94c84fcd18d448fbbc84af0' 
  AND token = 'Inr3wGD+Y0qNYFEYUAfXhpb8Rfm3WB1WniMoqmy+SM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}