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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e525309faf99631d41426f85e061c34024d728796b28d044d41e5e7f7d2498a0' 
  AND token = 'SYJA3kOsELD8QmenuRFjIS2QHaXtkNx9CZ5nL2PqQDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}