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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ebfc45ff8529bcd8d80ab4f6b41fa8eea83b104453b2b5ad57bf0bbde24d49f' 
  AND token = 'c2bAVoHYlQcyNrhHNqAmWDMFdJUsKAf9dfUD03GhT6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}