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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a18b5bea5f1fb52b24ea254eda810db1dc5c1d88b52235e2f28a7b42271611d' 
  AND token = 'Pf3NwMAlEJ9+sx2BTikwZw0XMifkjsRL0/ToENMl6+8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}