SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b901d5b220a03114a1f601179fe9aa06c5eabe2cf9cde6b6c8e38f7b76c3a705' 
  AND token = 'mw0KP7z31O6rvFM8dGSMAxLmxHIBXdyorQIBdVUxJCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}