SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51e44e73dbe63bd0f0e8f3872bc74de3c29aaee64c80c5b339610fc064384229' 
  AND token = 'cvs85BT6sxU9o64wLc1ZuaVJM7zO0W1c0VfXThXE8aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}