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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626a9b3a0a2b5d4b13d49e1ae831186c72667857e5630e084a2c421927851d14' 
  AND token = 'A6HWWBFJyuxZNsKOn42mqNIfVRKdrvZuCW8TIg9O1IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}