SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f7d67bad7c371d9f66db4381116981ddcc8e3325757a24650e1b99578480aee' 
  AND token = 'lRlj1Xi1Lb3IoRmZty4AasxOrZXn9BfTJOY2qmlR9Wc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}