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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ee99b7e12ed355d7f71cb118d4412871660143c6abf797f8ae9a652495ebc12' 
  AND token = 'QeBz0YfDfKkoeioIpDC2e6ypp96LUHDCZ/EQOxFTDYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}