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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12b6619b65357756592c3db565e4531509c0c45b256d9658d1a25285d81fa1ca' 
  AND token = 'NHFDIn39bH+KawOj1+9LcS4lDuOER1Py0mICEj+UWDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}