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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3324d57bf57e744eec7fc2d559a227180b32d826dd1fb8f54e3a14a1bbf0ebf' 
  AND token = '+SX6flN5J+Owrd5ta917f4c7KPfDEXDSRq6Sm2UKfVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}