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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33593bcf3fd121167680339d3467d6e0eb9ff4588733d52a3a01edeece4dced6' 
  AND token = '+7pqD9TlNovLGZOAem5ggQAch/uET6dIe9V4pLn1ck8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}