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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5931de3d6bce1052b20bdda8c4fbea9086e2b39b02206c52828799592ef2d47' 
  AND token = 'en3+D2mBwnPynYjwRgOFK6D1cDea8rKfSvucDkBCMks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}