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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5abc6700eca7aa875c2c10b5a0978ce1a2d4a3f644afbf90bf851f805d350444' 
  AND token = 'mdX77YW/8JXFmrgxWJkr9wCRkM9hVCjyyfd5LhBLtQQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}