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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff9481bbd2741ddb24233b79c8ddf408ba3496c8ad591d9bc1be6cdc76db7b77' 
  AND token = '29N461HTLEijHhNURGjnzqG4xhwTwBEl73/OJS24ARY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}