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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '945c7de495a3fffd5f1c9eb3c0bcf7e667be2b4f23156a88aa9aa67bac0c6f21' 
  AND token = 'JaNQB17KeAEL30pxnB99oFC1H8ACH6bQFE6rPgJrw9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}