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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57fee64ac3c739f80886377d3b1ce187c4c745339d7625b804e71a6ad9f5f238' 
  AND token = 'p/CTThcaHMOs5y7uPr8I2dExspK+uqzlvLGdyEL4khg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}