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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d88699d2d97ee724324ba1cef03cb03be9812307d01d79dfc96fb99cde8f59d' 
  AND token = 'dFuyfg2BcHlFsa3tZQ1N5HUumDdMtDfzYlFt+PUtMgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}