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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b300fc54da3d21a07fe815c775840337bfba7d1849985763c757a899a801d496' 
  AND token = '56+THczlLn0bgXept5OwRBGXJhdImYybJnKaPN738eY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}