SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c357e2d0f69c22013d9ddd56e1b95ea8c1dc7bcadca213cf9477f15829e71507' 
  AND token = 'r1VlkfGuJXa0zps3dkd4AJHNNVlwTBYv6jEwW1vFtgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}