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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522063dc0037e8e0092c7c200abbd41c3a27345e5a0b4fdeb0f6221c8f27c455' 
  AND token = 'FeiN/nnZ9KKN+M4hOfusRVU9pf1tozmO4UG6CAF10Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}