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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf4106532d076d42061907a55f83e1c667c344b29fe1c6bc3be6bbd0b80c1452' 
  AND token = 'CHxX4q98ojrCGo5IMmBeIisBN8S7KLCOwIsDv+dtTjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}