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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2043ad47a56ccb41fb3462e48b9620ff5b922df27dcbac7f6a7eaade2fb237' 
  AND token = '9t1ERF2ddEjGT3/LAqXnZE1hYjol+6Kw7fL6TkTlRt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}