SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1344fd5d6f0e9ac816e7d5473014ea4137116c5c4531466dd84a3a5ffc90da7d' 
  AND token = '3MKVb1IidFnXp1xz9wz1/lNC7b+1oOpVwmh4e3MTbjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}