SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380a49d119de2d32592418f68e3d8c27da2d32acc70bf77a616a238b294ec327' 
  AND token = 'zUxYN4pdsei1Ub69KgDHtzcRGNCJG1uFZ2ma2RCWI7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}