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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5be0cf1b093c74c5a2dedd0d1c43428653ff17b7a9d5681bbdca80ce1fdbbdcc' 
  AND token = 't/DCiypJisQXPvtZmQWK40qyAB5S803/ayW8jpg5ZSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}