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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cee672e44fa70d9a2e82050dd88430d70608325e93f4a8a00644836e721cc130' 
  AND token = 'RDHFSHgV5qa3cssX+k0T/C5jRVN8/p5FceaEBDavjXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}