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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e57d9c4209b988d8f83fa5b949cf135e947455e9b7bee20c0803d3622b6ea14' 
  AND token = 'R/1PxnB5jkUevHT73N9tNKMRn7TllShzRmJUKvEs0XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}