SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8120f7b5f8969ed7e9fc872d5369c8bae0cd234ca57c95775af412ca73edfcbe' 
  AND token = 'B0aNplWQxcz7O5A6BI4VgnGsdr1aZpWAhAwsZG+XrmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}