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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eed9645a20ed4d293c46c4babe3dee7ac9a717707953372813ce5fe4904ac71' 
  AND token = 'ZSVj1q4BOFnOHV8q4Ww9y+OY7CW0K1lI71jh93vbcAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}