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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3de1163e73f7061e9f0ddfc2754624aa22ccaf82fd23b2121cbc07d9739e91e2' 
  AND token = '4i8tR5EccaXE02P1lCOQo3ECtQAT5GyPYWiCLu5Ygu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}