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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859a212f232a573b0b3312bf5cbefe0bf7513b8f1886eeddb60c84b79e74aa3b' 
  AND token = 'Kw+RGrwdeBYBEI/nMGiv0enAVQiIRlq28o8LcftWofA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}