SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7303c0e3a0cdaf8cc61b6e39c3a237bdab1e85bd9b0f03ef5a7da497692e0707' 
  AND token = 'NNA7GyfDR0mYBxjL/EjmR5OcHOR/9ir2zYneM8JO0XA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}