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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0521f71e63ada462119dc0325f0df211c19dcc1ace50c23b666a68aae3244a84' 
  AND token = 'iW5U6b2mgRzxtijjDt3zRvjz6z4iJG3f/sow6wl4p9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}